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NMN, a naturally occurring compound, plays a crucial role in the production of nicotinamide adenine dinucleotide (NAD+), a coenzyme vital for various biological processes in the body, including energy metabolism, DNA repair, and cellular signaling. 

Although NMN is present in modest quantities in foods like broccoli, avocados, and cucumbers, its anti-aging potential and its ability to extend lifespan and promote longevity have led many individuals to opt for NMN supplementation to enhance their NAD+ levels and bolster overall health.

One capsule contains 500 mg of NMN. A two-capsule serving provides 1000 mg.
Recommended dosage:
40-50 years - 1 capsule per day;
50 years and more - 2 capsules per day

Recommendations: Take one or two capsules daily. To maximize absorption, take on an empty stomach in the morning, preferably 1 hour before breakfast.

NMN is a precursor to NAD+ and is quickly converted to NAD+ when ingested. By increasing NAD+ levels, NMN may help support healthy aging and promote longevity by supporting various cellular processes. Research suggests that NMN may have a wide range of health benefits, including:

Promote healthy aging and longevity: NMN has been shown to promote healthy aging by improving overall health and vitality, supporting healthy cellular function, and reducing the risk of age-related diseases. In animal studies, NMN supplementation suppressed age-associated body weight gain, enhanced energy metabolism, promoted physical activity, improved insulin sensitivity and plasma lipid profile, and ameliorated eye function and other age-related decline². Research continues to demonstrate the ability of NMN supplementation to increase life span in many animal models of aging^3,4, suggesting that it may have similar benefits in humans.

Supports DNA repair: NMN also plays a role in repairing damaged DNA through its function in NAD+-dependent enzymes, including the Sirtuin family⁴. DNA repair is important for maintaining healthy cellular function and preventing the development of age-related conditions.

Enhances cognitive function: As we age, cognitive decline is a common concern. NMN has been shown to improve cognitive function in animal studies⁵, suggesting that it may have similar benefits in humans.

Supports cardiovascular health: NMN may also support cardiovascular health by improving endothelial function, reducing inflammation, and reducing oxidative stress^6–8.

Improves insulin sensitivity: Insulin resistance is a common problem as we age, but NMN may help improve insulin sensitivity and support healthy glucose metabolism^9–11.

Improving health and longevity depends on individual factors such as age, diet, and lifestyle. To maximise the benefits of our supplements, we recommend incorporating them into a comprehensive anti-aging regimen that includes healthy eating, regular exercise, and other lifestyle factors that promote longevity and healthy aging.

1. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22(2):119-141. doi:10.1038/s41580-020-00313-x

2. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013

3. Zhang H, Ryu D, Wu Y, et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016;352(6292):1436-1443. doi:10.1126/science.aaf2693

4. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004

5. Gong B, Pan Y, Vempati P, et al. Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer’s mouse models. Neurobiol Aging. 2013;34(6):1581-1588. doi:10.1016/j.neurobiolaging.2012.12.005

6. de Picciotto NE, Gano LB, Johnson LC, et al. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell. 2016;15(3):522-530. doi:10.1111/acel.12461

7. Zhang R, Shen Y, Zhou L, et al. Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure. J Mol Cell Cardiol. 2017;112:64-73. doi:10.1016/j.yjmcc.2017.09.001

8. Zhang X, Zhang Y, Sun A, Ge J. The effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential. Genes Dis. 2022;9(4):959-972. doi:10.1016/j.gendis.2021.04.001

9. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

10. Yoshino J, Mills KF, Yoon MJ, Imai S ichiro. Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528. doi:10.1016/j.cmet.2011.08.014

11. Roos J, Zinngrebe J, Fischer-Posovszky P. Nicotinamide mononucleotide: a potential effective natural compound against insulin resistance. Signal Transduct Target Ther. 2021;6(1):1-2. doi:10.1038/s41392-021-00723-z