MASI Longevity Science

Premium Resveratrol & Grape Seed Extract

Activates your body’s longevity genes

Resveratrol · Grape seed · Selenium

4.9 from 1,000+ reviews 1.37M+ servings
resveratrol per serving
500 mg
made in Germany
Germany
independently tested
Swiss lab
See the Swiss lab reports

Powerful antioxidant that activates the youth gene Sirtuin 1 for DNA repair, protects the brain from age-related diseases, and lowers the risk of cancer. MASI Premium Resveratrol is physician-formulated and backed by human clinical research to target the root causes of aging:

Supports cellular antioxidant defense

Powerful antioxidant
protection.

  • Improves blood vessel functionStudy
  • Boosts memory and brain performanceStudy
  • Improves bone strength and densityStudy

How many adults?

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Purchase option

30-day supply, billed every 28 days (4 weeks).One-time purchase. No recurring payment.

Renews at €95.37 every 4 weeks. Cancel anytime.

Fast, insured delivery No import duties

Made in Germany
Third-party tested in Switzerland
Batch quality reports available

Product details

What is RESVERATROL?

Sirtuin 1, key for youthfulness, declines with age, accelerating aging. It's vital for DNA repair, reducing inflammation, and antioxidant defense. MASI's Premium Resveratrol reactivates Sirtuin 1, bolstering anti-aging defenses for extended youth. Paired with NMN, its anti-aging impact intensifies, offering optimal benefits.

Resveratrol has been linked to lowering cancer risk. This is because resveratrol has anti-tumor properties, and it's able to inhibit cancer formation at all stages of development: "initiation, promotion, and progression."

✓ Activates Sirtuin 1, slowing aging in cells

✓ Provides powerful antioxidant protection against oxidative stress

✓ Enhances overall cardiovascular health

✓ Protects the brain from age-related diseases

Resveratrol, a natural plant compound falling under the category of polyphenols, can be found in various fruits like grapes and berries. It is particularly abundant in the skin of red grapes and red wine. Resveratrol is synthesized by plants as a response to stress and injury, serving as a protective mechanism for the plant, and this protective effect is thought to be transferable to humans when consumed. However, the quantity of resveratrol in red wine is relatively modest. 

Achieving the anti-aging and longevity benefits associated with resveratrol would require consuming such large quantities of wine that the adverse health effects linked to excessive alcohol intake would largely negate any potential advantages from resveratrol. Therefore, supplementing with isolated resveratrol provides a convenient and healthy means to harness its properties for reversing aging and promoting longevity.

Dosing
One capsule contains:

  • 250mg Resveratrol,
  • 300mg of Grape seed extract,
  • 20ug Selenium

Recommended dosage:
40-50 years - 1 capsule per day;
50 years and more - 2 capsules per day

Recommendations: Take one or two capsules daily, preferably with a standard breakfast.

Serving & supply

Each jar contains 60 capsules. One capsule contains 250 mg resveratrol, 300 mg grape seed extract, and 20 µg selenium. At two capsules daily, one jar lasts 30 days. At one capsule daily, it lasts up to 60 days.

Resveratrol Benefits
Resveratrol is one of the leading longevity molecules due to its potent antioxidant properties and anti-aging effects2. Antioxidants are substances that help to protect your cells from damage caused by harmful molecules known as free radicals, which can accumulate in the body and cause oxidative stress.

Oxidative stress is thought to play a key role in the aging process, contributing to cellular damage, inflammation, and a range of age-related health issues. By neutralising free radicals and reducing oxidative stress, resveratrol may help to promote healthy aging and delay the onset of age-related diseases3–5.

Resveratrol has also been shown to activate a gene known as SIRT1, which plays a key role in regulating cellular processes related to aging, including DNA repair, inflammation, and metabolism. By activating this gene, resveratrol has been shown to promote healthy aging and increase lifespan2,6–8.

Other potential anti-aging effects of resveratrol include improved cardiovascular health, enhanced immune function, and reduced inflammation, all of which can help to promote overall health and longevity9,10. While more research is needed to fully understand the anti-aging effects of resveratrol in humans, studies in animal models of aging report that resveratrol is one of the leading compounds for promoting healthy aging and delaying age-related diseases.

Please note that results may vary depending on individual factors such as age, diet, and lifestyle. To maximise the benefits of our supplements, we recommend incorporating them into a comprehensive anti-aging regimen that includes healthy eating, regular exercise, and other lifestyle factors that promote longevity and healthy aging.

Studies & ingredient research

  • Improves blood vessel functionStudy
  • Boosts memory and brain performanceStudy
  • Improves bone strength and densityStudy
  • Supports healthy blood sugar balanceStudy
  • Lowers LDL cholesterolStudy
  • Reduces inflammation at the genetic levelStudy
  • Protects the liver and improves metabolic healthStudy
  • Activates your body’s longevity genesStudy
  • Clinically proven safe even at high dosesStudy
  • Improves blood flow to the brainStudy
References
1. la Porte C, Voduc N, Zhang G, et al. Steady-State Pharmacokinetics and Tolerability of Trans-Resveratrol 2000mg Twice Daily with Food, Quercetin and Alcohol (Ethanol) in Healthy Human Subjects. Clin Pharmacokinet. 2010;49(7):449-454. doi:10.2165/11531820-000000000-00000


2. Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 2006;5(6):493-506. doi:10.1038/nrd2060


3. Cosín-Tomàs M, Senserrich J, Arumí-Planas M, et al. Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease Patients. Nutrients. 2019;11(8):1764. doi:10.3390/nu11081764


4. Gu T, Wang N, Wu T, Ge Q, Chen L. Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis. J Food Qual. 2021;2021:e5571733. doi:10.1155/2021/5571733


5. Liu T, Qi H, Ma L, et al. Resveratrol Attenuates Oxidative Stress and Extends Life Span in the Annual Fish Nothobranchius guentheri. Rejuvenation Res. 2015;18(3):225-233. doi:10.1089/rej.2014.1618


6. Bhullar KS, Hubbard BP. Lifespan and healthspan extension by resveratrol. Biochim Biophys Acta BBA - Mol Basis Dis. 2015;1852(6):1209-1218. doi:10.1016/j.bbadis.2015.01.012


7. Morselli E, Maiuri MC, Markaki M, et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis. 2010;1(1):e10. doi:10.1038/cddis.2009.8


8. Kt H, Kj B, Hy C, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003;425(6954). doi:10.1038/nature01960


9. L M. Influence of Resveratrol on the Immune Response. Nutrients. 2019;11(5). doi:10.3390/nu11050946


10. Petrovski G, Gurusamy N, Das DK. Resveratrol in cardiovascular health and disease. Ann N Y Acad Sci. 2011;1215(1):22-33. doi:10.1111/j.1749-6632.2010.05843.x


11. Singh CK, George J, Ahmad N. Resveratrol-based combinatorial strategies for cancer management. Ann N Y Acad Sci. 2013;1290(1):113. doi:10.1111/nyas.12160


12. Singh CK, Liu X, Ahmad N. Resveratrol, in its natural combination in whole grape, for health promotion and disease management. Ann N Y Acad Sci. 2015;1348(1):150. doi:10.1111/nyas.12798


13. Cai Z, Zhang J, Li H. Selenium, aging and aging-related diseases. Aging Clin Exp Res. 2019;31(8):1035-1047. doi:10.1007/s40520-018-1086-7

14.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514220/#:~:text=However%2C%20age%2Drelated%20decrease%20in,senescence%2Fanti%2Dageing%20targets.

Swiss lab reports & quality
Swiss lab testingPremium Resveratrol · Product-specific reports

Check the batch on your packaging against the report. Review the tests listed below for your batch.

Resveratrol Purity test ↗
Resveratrol Microbiology test ↗
Resveratrol Heavy metal test ↗

What real members say
about Premium Resveratrol.

★★★★★

Keeps me going

I’m 64 and resveratrol has been a great addition to my daily supplement cycle. I have a garden, and I’ve been able to spend more time tending to it without getting tired.

Teresa K

★★★★★

Works great with other supplements

I’ve been taking NMN and Resveratrol from MASI for a while now and the combined effect has been a life changer. My profession requires me to travel a lot and these 2 supplements have provided me with the much needed energy throughout my travels.

Leo

★★★★★

MASI resveratrol-enhanced formula is a game-changer, feeling rejuvenated and my skin looks notice...

Ever since I started using this supplement with resveratrol, I've noticed a significant boost in my energy and skin radiance. I did my homework on anti-aging products and this one stood out.…

Ethan

★★★★★

Since starting this supplement with resveratrol, I've experienced a significant boost in energy a...

I was looking for something simple yet effective, and this supplement fits the bill perfectly. It's amazing how well it works. I've tried other products, but this one stands out for its efficacy.…

Jack

Healthy aging is correlated with Resveratrol's influence on cellular and molecular pathways.

What is Resveratrol?

Resveratrol, also known as 3,5,4'-trihydroxy-trans-stilbene, is a plant-derived polyphenol that helps protect
against environmental stressors
like extreme weather and insect attacks. Found mainly in red grape skins, it also occurs in peanuts, blueberries, raspberries, mulberries, and Japanese knotweed (Hu Zhang). It's known for stimulating sirtuins, genes linked to longevity and DNA protection, and works synergistically with NAD+ enhancers like NMN.

Harvard's David Sinclair has extensively researched Resveratrol, focusing on its potential to counteract aging effects. It works by managing oxidative stress, altering energy metabolism, and regulating nutrient sensing and epigenetics, primarily through activating sirtuin 1, which may increase lifespan.

Resveratrol

Your daily routine

Increase antioxidants and cardiovascular health in just 30 days.

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“I'm convinced that MASI supplements enhance cellular health and address several aging-related issues. It's a key component of my overall longevity strategy. This strategy includes MASI, regular exercise and a balanced diet, all working together to support a vibrant and healthy life in the years to come.”

Dr.Wolfgang Bucke, Ph.D.,Senior Pharmacist and Board Member

Pure transparency

From source to capsule.

See each step, from ingredients to delivery.

About our process

MASI is the only line of longevity supplements featuring 100% German materials & engineering.

MASI prioritizes honesty and transparency.
While most companies vaguely claim
"made in [country]" without proof, we openly share our entire process. Ensuring our customers have the full, verifiable story.

  1. Sourced in Germany

    MASI proudly upholds an unwavering standard by utilizing 100% German raw materials, ensuring zero components are sourced from China. This commitment harnesses the renowned high-quality German engineering, merging meticulous craftsmanship with stringent quality controls. Our dedication to sourcing exclusively within Germany guarantees that each product not only meets but exceeds expectations, offering a synergy of superior engineering and absolute purity, unmatched in the realm of NMN brands.

  2. Produced in Germany

    MASI's commitment to superior longevity supplements is rooted in our pharmaceutical-grade German facilities. Each product stands as a testament to unmatched quality and purity, crafted through an advanced enzymatic process, not chemicals, ensuring a pristine formula. Ingredients and dietary suitability vary by product. Check each product page for ingredient and allergen information.

  3. Encapsulated in Germany

    Meticulously crafted, our capsules represent the pinnacle of purity and environmental responsibility, sourced from sustainable German pine tree extract. Advanced precision technology ensures consistent dosages for reliable efficacy, while the thoughtfully engineered composition maximizes bioavailability and digestibility, offering a gentle touch on your digestive system. These 100% vegan capsules reflect our commitment to delivering safe, effective health solutions, encapsulating the essence of Germany's botanical treasures in a pristine, contaminant-free process, for a superior, stomach-friendly wellness experience

  4. Tested in Switzerland

    Our products are rigorously third-party tested in Swiss laboratories, including independent verification by an accredited facility, ensuring unmatched standards of purity and safety. Each batch is meticulously analyzed for purity, microbiology—to detect and eliminate harmful microorganisms—and heavy metals like lead, mercury, and cadmium. This comprehensive testing assures the hygiene, purity, and utmost safety of our supplements, reflecting our commitment to delivering contaminant-free, trusted wellness solutions in every pristine batch

  5. Bottled in Germany

    Ensuring precision in every capsule, our supplements are bottled in a pharmaceutical-grade facility in Germany, renowned for its meticulous standards. This process guarantees exact product amounts in each capsule, upheld by rigorous quality controls for unmatched consistency. This commitment to precision, coupled with our adherence to the highest standards of safety and purity, ensures that every dose delivers the trusted, effective wellness solutions our customers expect

  6. Shipped from Europe

    Leveraging multiple European facilities, our shipping process ensures exceptionally fast product arrival at minimal costs. With our expansion, new satellite facilities in Australia and the United States further enhance our efficiency, promising speedier delivery, economical rates, and straightforward returns. This robust network guarantees not just swift, but also cost-effective and convenient service, making each order a testament to our commitment to unparalleled customer satisfaction

Lab Results

100% resveratrol purity in the tested batch.

Read the independent Swiss laboratory reports below. Each report applies to its stated product and batch.

Who should be taking anti-aging supplements?

  • Age 30-45, notices the body's evolving needs, observing the emergence of wrinkles and fine lines, sensing emotional reactions to aging and experiencing a decline in energy and memory.

  • Science-based thinkiners, motivated by scientific research and discoveries, fascinated by the pursuit of graceful aging and longevity, dedicated to investing time and resources in anti-aging strategies.

  • Advocates for healthy lifestyle choices, strongly focused on a nutritious diet and regular exercise, committed to proactive change and the use of supplements for well-being.

  • Age 45-80, visible signs of aging, decline in skin elasticity and firmness, increases physical fatigue, memory lapses, mild to extreme cognitive decline, pursuing enhancements in the essential years, aspiring for overall well-being.

Your personalised plan · 1-minute quiz

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  • Fast shipping

    Orders placed before 22:00 are shipped the same day

  • No import duties

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  • Easy returns

    Money back within the first 14 days

Frequently Asked Questions

What is Resveratrol?

Resveratrol is a natural compound found in red wine and certain fruits, known for its antioxidant and anti-inflammatory properties.

How does Resveratrol promote anti-aging?

Resveratrol activates certain genes that ward off the diseases of aging, potentially extending lifespan and improving health.

Can Resveratrol reverse signs of aging?

Resveratrol can't reverse aging but may help slow its progression and mitigate some age-related health issues.

Is Resveratrol safe to take?

Resveratrol is generally safe when taken in moderate amounts; however, it's best to consult with a healthcare professional.

What is the recommended dosage for Resveratrol supplements?

Dosages can vary; the optimal daily dosage of Resveratrol 250mg for ages 50 and under and 500mg for ages 50 and over.

Are there any side effects of taking Resveratrol?

Side effects are rare but can include digestive issues; high doses might lead to more serious effects.

Can Resveratrol supplements be taken with other medications?

As with any supplement, check with a healthcare provider for potential interactions with other medications.

How long does it take to see the effects of Resveratrol supplements?

Effects can vary; consistent, long-term use is typically required to notice health benefits.

Who should avoid taking Resveratrol supplements?

Pregnant or breastfeeding women, individuals with hormone-sensitive conditions, or those on certain medications should consult a doctor first.

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