MASI Longevity Science
Miracle NAD booster + cancer cell fighter.
1000 mg NMN + 500 mg Fisetin · two capsules of each, daily
1.37M+ servingsThe miracle NAD booster, now paired with a cancer cell fighter.
MASI Premium NMN refuels NAD+, the cell fuel you lose with age, so you wake up young every morning.
MASI Premium Fisetin fights the formation of cancer cells and clears senescent "zombie" cells.
Renews at $368.95 every 4 weeks. Cancel anytime
Fast, insured delivery · No import duties
One full-size jar of Premium NMN and one full-size jar of Premium Fisetin. Each jar contains 60 capsules.
NAD+ is a compound found in every cell. It helps power cellular energy and supports metabolic reactions. NMN is a precursor to NAD+, whose levels decline with age.
Senescent cells have stopped dividing and no longer function properly. They can accumulate with age. Fisetin is a natural flavonoid studied for its ability to target these cells.
Two NMN capsules provide 1000 mg. Two Fisetin capsules provide 500 mg. At two capsules of each formula daily, each jar provides a 30-day supply. Follow the directions on each product label. Subscription delivery repeats every 28 days.
One capsule contains 500 mg of NMN. The current product directions recommend one or two capsules daily, in the morning on an empty stomach, preferably one hour before breakfast. Follow your product label.
One capsule contains 250 mg of Fisetin. A two-capsule serving provides 500 mg. Follow the directions on your Fisetin product label.
Fisetin cancer findings concern laboratory research. They do not establish that this supplement prevents or treats cancer. Trial registrations describe research plans, not proven benefits.
NMN is a precursor to NAD+ and is quickly converted to NAD+ when ingested. By increasing NAD+ levels, NMN may help support healthy aging and promote longevity by supporting various cellular processes. Research suggests that NMN may have a wide range of health benefits, including:
Promote healthy aging and longevity: NMN has been shown to promote healthy aging by improving overall health and vitality, supporting healthy cellular function, and reducing the risk of age-related diseases. In animal studies, NMN supplementation suppressed age-associated body weight gain, enhanced energy metabolism, promoted physical activity, improved insulin sensitivity and plasma lipid profile, and ameliorated eye function and other age-related decline2. Research continues to demonstrate the ability of NMN supplementation to increase life span in many animal models of aging3,4, suggesting that it may have similar benefits in humans.
Supports DNA repair: NMN also plays a role in repairing damaged DNA through its function in NAD+-dependent enzymes, including the Sirtuin family4. DNA repair is important for maintaining healthy cellular function and preventing the development of age-related conditions.
Enhances cognitive function: As we age, cognitive decline is a common concern. NMN has been shown to improve cognitive function in animal studies5, suggesting that it may have similar benefits in humans.
Supports cardiovascular health: NMN may also support cardiovascular health by improving endothelial function, reducing inflammation, and reducing oxidative stress6–8.
Improves insulin sensitivity: Insulin resistance is a common problem as we age, but NMN may help improve insulin sensitivity and support healthy glucose metabolism9–11.
Improving health and longevity depends on individual factors such as age, diet, and lifestyle. To maximise the benefits of our supplements, we recommend incorporating them into a comprehensive anti-aging regimen that includes healthy eating, regular exercise, and other lifestyle factors that promote longevity and healthy aging.
1. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22(2):119-141. doi:10.1038/s41580-020-00313-x
2. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013
3. Zhang H, Ryu D, Wu Y, et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016;352(6292):1436-1443. doi:10.1126/science.aaf2693
4. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004
5. Gong B, Pan Y, Vempati P, et al. Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer’s mouse models. Neurobiol Aging. 2013;34(6):1581-1588. doi:10.1016/j.neurobiolaging.2012.12.005
6. de Picciotto NE, Gano LB, Johnson LC, et al. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell. 2016;15(3):522-530. doi:10.1111/acel.12461
7. Zhang R, Shen Y, Zhou L, et al. Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure. J Mol Cell Cardiol. 2017;112:64-73. doi:10.1016/j.yjmcc.2017.09.001
8. Zhang X, Zhang Y, Sun A, Ge J. The effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential. Genes Dis. 2022;9(4):959-972. doi:10.1016/j.gendis.2021.04.001
9. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985
10. Yoshino J, Mills KF, Yoon MJ, Imai S ichiro. Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528. doi:10.1016/j.cmet.2011.08.014
11. Roos J, Zinngrebe J, Fischer-Posovszky P. Nicotinamide mononucleotide: a potential effective natural compound against insulin resistance. Signal Transduct Target Ther. 2021;6(1):1-2. doi:10.1038/s41392-021-00723-z
Read the Swiss lab reports for each product and tested batch. Each report shows the analyses performed.
Fisetin purity testing is currently excluded. The linked Fisetin reports cover microbiology and heavy metals.
See the Swiss lab resultsMASI customer experiences with NMN and Fisetin. These reviews relate to the individual formulas.
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I've been taking MASI NMN for more than a year and the difference in my daily energy is noticeable. I used to take Lion's mane, l-theanine and other well-known supplements but for me, MASI NMN has been the most useful one in my routine at my age. I pair it with lower doses of caffeine and feel I get more done day to day. A brand I feel safe taking.
Lotte
NMN customer experience
I like fisetin, I can feel my skin and body different than other supplements
Roman
Fisetin customer experience
It is my recommendation that anyone over 40 years of age looks into NMN. Clinical studies have shown it can support NAD+ — the cellular co-factor involved in energy production, which naturally declines with age. NMN, as a precursor, is well-studied for replenishing those NAD+ levels and supporting healthy-aging biomarkers. Great work from MASI, the highest-quality NMN I've tested.
Christian
NMN customer experience
Fisetin has helped reduce the general aches and stiffness I’ve been feeling as I’ve gotten older. It’s become a key part of my health routine now.
Isak U
Fisetin customer experience
Healthy aging, from within
NMN supports daily NAD+. Fisetin targets senescent cells. Each has its own role in your healthy-aging routine.
Premium NMN
Increases energy levels
Read studyImproves sleep quality
Read studySupports daily performance
Read studyPremium Fisetin
Helps clear senescent cells
Trial registrationBoosts antioxidant defense
Read studySupports healthy metabolism
Trial registrationStudy links concern the individual ingredients. They do not establish an additional benefit from this combination. Clinical trial links identify registered research.
Healthy aging is linked to NAD+ levels
Research featured in the prestigious journal Nature Aging indicates a significant correlation between levels of NAD+ and overall health during human aging.
NAD+, short for nicotinamide adenine dinucleotide, is a critical compound present in every cell of the human body. This molecule plays a vital role in numerous biological processes, acting as a key player in the metabolic reactions that power our cells and, by extension, our entire bodies. Its presence and function are fundamental to maintaining cellular vitality.
Nicotinamide
Adenine
Dinucleotide
Studies indicate that starting anti-aging efforts in your 30's is optimal. Incorporating NAD+ enhancers like NMN into your daily regimen can rejuvenate NAD+ levels to what they were in your 20's, effectively aiding in the anti-aging process.
Renowned Harvard scientist David Sinclair defends this stance with his research, highlighting the critical role of sirtuins - a family of proteins that depend on NAD+ and are essential for cellular health. Sirtuins regulate cellular processes like DNA repair, inflammation reduction, and mitochondrial function. NMN, a precursor to NAD+, is crucial in this process as it helps replenish declining NAD+ levels, effectively rejuvenating cells and mirroring the vitality experienced in one’s 20s.
Sinclair’s studies affirm the significant impact of NAD+ and NMN in promoting longevity and combating the signs of aging.
Age in years
Fisetin · Senescent cells
Fisetin, a flavonoid naturally present in fruits like strawberries. Its origin from plants has led to research on its anti-aging applications. One of its key functions is the reduction of senescent cells, which are linked to aging and degenerative diseases. Studies indicate fisetin can extend lifespan in certain models by up to 10%, emphasizing its role in aging.
Additionally, it acts as a potent antioxidant, addressing oxidative stress, a major factor in the aging process. It also supports brain health, potentially reducing the incidence of neurodegenerative conditions. David Sinclair, a renowned longevity scientist, incorporates 500mg of fisetin into his supplement regimen, highlighting its importance in promoting healthy aging. Fisetin's multifaceted approach to aging, from senescent cells also known as "zombie cells" that no longer divide but accumulate as we age, causing various health issues. It's like a cleanup crew, removing these cells to promote healthier aging.
“I'm convinced that MASI supplements enhance cellular health and address several aging-related issues. It's a key component of my overall longevity strategy. This strategy includes MASI, regular exercise and a balanced diet, all working together to support a vibrant and healthy life in the years to come.”
Your two-formula routine
You receive the same Premium NMN and Premium Fisetin formulas available individually. Each keeps its own dose and product instructions.
Premium NMN
per two-capsule serving
One capsule contains 500 mg of NMN. The current product directions recommend one or two capsules daily, in the morning on an empty stomach, preferably one hour before breakfast. Follow your product label.
Premium Fisetin
per two-capsule serving
One capsule contains 250 mg of Fisetin. A two-capsule serving provides 500 mg. Follow the directions on your Fisetin product label.
These serving figures describe each formula separately. They are not a new combined dosage recommendation.
From Day 1 to Day 365
Your body is already elevating NAD+ levels at the cellular scale.
This internal increase is boosting cellular vitality and initiating the renewal process, serving as crucial upkeep for your proteome and genome, including mechanisms to defend against oxidative damage and stress.
You've reached a pivotal milestone.
Your cellular NAD+ levels have increased by +100%. Continuing with MASI NMN will help maintain these elevated levels, marking the start of significant changes. With sustained NMN intake, your body begins to adapt, particularly in the heart and brain, you will experience transformations.
Your body has been at an elevated NAD+ level for 30 days.
The NAD+ in your body is enhancing your heart's cellular energy, crucial for its continuous beating. It's actively fighting oxidative stress and reducing inflammation, key factors in heart health. Simultaneously, it's aiding in the repair of your heart cells.
You’re at the 6 month mark.
Your most notable improvement is the cellular energy in your brain, which is crucial for cognitive functions like memory and acuity. This increase in NAD+ is actively supporting your neurons, boosting the energy metabolism within your brain cells, maintaining and improving your mental acuity and memory functions.
Well done, you’ve completed 365 days of MASI NMN.
This marks just the beginning of your graceful aging journey. Your choice to integrate a balanced diet, regular exercise, mental stimulation, and supplementation has set a strong foundation for a fulfilling future. Keep building on this path of healthy aging and longevity, continually expanding your knowledge and nurturing your well-being.
Pure transparency
See each step, from ingredients to delivery.
MASI is the only line of longevity supplements featuring 100% German materials & engineering.
MASI prioritizes honesty and transparency.
While most companies vaguely claim
"made in [country]" without proof, we openly share our entire process. Ensuring our customers have the full, verifiable story.
MASI proudly upholds an unwavering standard by utilizing 100% German raw materials, ensuring zero components are sourced from China. This commitment harnesses the renowned high-quality German engineering, merging meticulous craftsmanship with stringent quality controls. Our dedication to sourcing exclusively within Germany guarantees that each product not only meets but exceeds expectations, offering a synergy of superior engineering and absolute purity, unmatched in the realm of NMN brands.
MASI's commitment to superior longevity supplements is rooted in our pharmaceutical-grade German facilities. Each product stands as a testament to unmatched quality and purity, crafted through an advanced enzymatic process, not chemicals, ensuring a pristine formula. Ingredients and dietary suitability vary by product. Check each product page for ingredient and allergen information.
Meticulously crafted, our capsules represent the pinnacle of purity and environmental responsibility, sourced from sustainable German pine tree extract. Advanced precision technology ensures consistent dosages for reliable efficacy, while the thoughtfully engineered composition maximizes bioavailability and digestibility, offering a gentle touch on your digestive system. These 100% vegan capsules reflect our commitment to delivering safe, effective health solutions, encapsulating the essence of Germany's botanical treasures in a pristine, contaminant-free process, for a superior, stomach-friendly wellness experience
Our products are rigorously third-party tested in Swiss laboratories, including independent verification by an accredited facility, ensuring unmatched standards of purity and safety. Each batch is meticulously analyzed for purity, microbiology—to detect and eliminate harmful microorganisms—and heavy metals like lead, mercury, and cadmium. This comprehensive testing assures the hygiene, purity, and utmost safety of our supplements, reflecting our commitment to delivering contaminant-free, trusted wellness solutions in every pristine batch
Ensuring precision in every capsule, our supplements are bottled in a pharmaceutical-grade facility in Germany, renowned for its meticulous standards. This process guarantees exact product amounts in each capsule, upheld by rigorous quality controls for unmatched consistency. This commitment to precision, coupled with our adherence to the highest standards of safety and purity, ensures that every dose delivers the trusted, effective wellness solutions our customers expect
Leveraging multiple European facilities, our shipping process ensures exceptionally fast product arrival at minimal costs. With our expansion, new satellite facilities in Australia and the United States further enhance our efficiency, promising speedier delivery, economical rates, and straightforward returns. This robust network guarantees not just swift, but also cost-effective and convenient service, making each order a testament to our commitment to unparalleled customer satisfaction
Lab Results
Read the independent Swiss laboratory reports below. Each report applies to its stated product and batch.
Read the Swiss lab reports for each product and tested batch. Each report shows the analyses performed.
Premium NMN
Purity · Lot MA0059
NMN Purity test
Microbiology · Lot MA3123
NMN Microbiology test
Heavy metals · Lot MA3123
NMN Heavy metal test
Premium Fisetin
Microbiology · Lot MA3323
Fisetin Microbiology test
Heavy metals · Lot MA3323
Fisetin Heavy metal test
Fisetin purity testing is currently excluded. The linked Fisetin reports cover microbiology and heavy metals.
The MASI standard
German materials and manufacturing, with strict quality controls.
Independent, product-specific lab reports you can read.
1000 mg NMN and 500 mg Fisetin per two-capsule serving of each product.
Plant-based capsules. Check each product label for the full ingredient list.
Orders placed before 22:00 are shipped the same day
For order outside the EU we got you covered
Money back within the first 14 days
Age 30-45, notices the body's evolving needs, observing the emergence of wrinkles and fine lines, sensing emotional reactions to aging and experiencing a decline in energy and memory.
Science-based thinkiners, motivated by scientific research and discoveries, fascinated by the pursuit of graceful aging and longevity, dedicated to investing time and resources in anti-aging strategies.
Advocates for healthy lifestyle choices, strongly focused on a nutritious diet and regular exercise, committed to proactive change and the use of supplements for well-being.
Age 45-80, visible signs of aging, decline in skin elasticity and firmness, increases physical fatigue, memory lapses, mild to extreme cognitive decline, pursuing enhancements in the essential years, aspiring for overall well-being.
Your personalised plan · 1-minute quiz
Take the 1 minute quiz to get your personalized MASI anti-aging plan
Know your routine
Review the contents, purchase options, and individual formulas before you choose.
Contact MASIOne jar of Premium NMN and one jar of Premium Fisetin. Each contains 60 capsules. Selecting two bundles gives you two jars of each formula.
The bundle subscription gives 10% total savings against the combined one-time component price. It is billed every 28 days, displayed as Every 4 weeks. The individual-product 5% and 10% tiers do not add to this discount.
Yes. One-time purchase has no subscription and no recurring payment. The bundle is priced at the combined one-time prices of its two products, without a bundle discount.
The linked studies concern NMN or Fisetin individually. They do not demonstrate an additional benefit from using this specific bundle. Each formula has its own research and product directions.
The lab-results section links to the Swiss reports for NMN and Fisetin. Check the tested batch and analysis on each report. Fisetin purity testing is currently excluded.
NMN (Nicotinamide Mononucleotide) is a precursor to NAD+, crucial for energy metabolism and cellular repair, potentially slowing aging processes.
NMN boosts NAD+ levels, supporting cellular energy production, DNA repair, and overall cell health.
Benefits may include improved energy levels, enhanced cognitive function, and potentially delayed aging signs.
Fisetin is a flavonoid compound with antioxidant properties, found in various fruits and vegetables.
Fisetin works by reducing oxidative stress and inflammation, potentially slowing down the aging process at the cellular level.
Yes, Fisetin has shown positive data for having anti-aging effects by promoting cellular health and longevity.
MASI Longevity Science
Premium NMN + Fisetin. Save 10% with a subscription every 4 weeks, or choose one-time purchase.
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